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Scientists have discovered a new genetic disease, which causes some children’s brains to develop abnormally, resulting in delayed intellectual development and often early onset cataracts. The majority of patients with the condition, which is so new it doesn’t have a name yet, we’re also microcephalic, a birth defect where a baby’s head is smaller than
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Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient’s own blood-forming stem cells. The trial will combine CRISPR technology developed at Innovative Genomics
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Researchers at Cincinnati Children’s Hospital Medical Center have developed a new framework for different factors influencing how a child’s brain is “wired” to learn to read before kindergarten. This may help pediatric providers identify risks when the brain is most responsive to experiences and interventions. This “eco-bio-developmental” model of emergent literacy, described in the journal
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Too often, contends UMass Lowell faculty researcher Brenna Morse, children with complex chronic medical conditions spend days in the hospital undergoing tests for what could be a simple diagnosis. The challenges include, she says, some children with medical complexities, such as severe neurological conditions and functional impairments, cannot easily signal that they are in pain
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About 61% of Americans have had at least one Adverse Childhood Experience (ACE), experts’ formal term for a traumatic childhood event. ACEs–which may include abuse, neglect and severe household dysfunction–often lead to psychological and social struggles that reach into adulthood, making ACEs a major public health challenge. But the long-term consequences of ACEs are just
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A review of more than 20 studies by researchers at Arizona State University and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggests that nonalcoholic fatty-liver disease (NAFLD) is a growing dietary problem for children across the globe. The prevalence of fatty-liver disease is escalating not only in adults, but also
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The massive and continuing outbreak of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), throughout the world, has led to a staggering toll of over 549,000 deaths in the USA, among over 30 million cases. A new preprint research paper posted to the medRxiv* server discusses the factors related
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The University of Illinois System, with a $1.4 million grant from The Rockefeller Foundation, announces the expansion of its SHIELD Illinois and SHIELD CU COVID-19 testing initiatives to help safely reopen underserved K-12 schools in communities across the state using the covidSHIELD test, an innovative, saliva-based test developed at the University of Illinois Urbana-Champaign (UIUC).
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