Children’s Health

A healthy system of gut bacteria, or microbiota, is crucial to health: Gut bacteria not only aid with digestion, but also play an important role in the body’s immune response. Infants, however, are not born with full-fledged gut microbiota, which makes it difficult for them to fight off intestinal infections. Although little is known about
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Utah researchers report significant new insights into the development of blood cancers. In work published today in Blood Cancer Discovery, a journal of the American Association for Cancer Research, scientists describe an analysis of published data from more than 7,000 patients diagnosed with leukemia and other blood disorders. Their findings provide new clues about mutations
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A new study of patients with Multisystem Inflammatory Syndrome in Children (MIS-C), a rare but severe complication of COVID-19 in children, reveals distinct immune features of COVID-19 not seen in adults that may clue scientists in to why SARS-CoV-2 infection manifests differently in children compared with adults. Their results showed that although the immune landscape
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Type 2 diabetes, once considered an adult disease, is increasingly causing health complications among American youth. A research review published in the Journal of Osteopathic Medicine suggests physicians should work to more aggressively prevent pediatric diabetes. Because few pediatric Type 2 diabetes treatment options are available, prevention is unusually important. To improve health outcomes, the
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Scientists at Cincinnati Children’s just received a 5-year grant totaling $5.3 million from the National Institute of Environmental Health Sciences (NIEHS) to advance research into the relationship between air pollution and mental health in children and adolescents. The grant will enable the scientists to conduct new air pollution exposure studies and analyze its impact on
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With Covid vaccines expected to remain scarce into early spring, Connecticut has scrapped its complicated plans to prioritize immunizations for people under 65 with certain chronic conditions and front-line workers. Instead, the state will primarily base eligibility on age. Gov. Ned Lamont pointed to statistics showing the risk of death and hospitalization from Covid-19 rises
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Medical researchers have long understood that a pregnant mother’s diet has a profound impact on her developing fetus’s immune system and that babies — especially those born prematurely — who are fed breast milk have a more robust ability to fight disease, suggesting that even after childbirth, a mother’s diet matters. However, the biological mechanisms
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Molecules called microRNAs (miRNAs) that are measurable in urine have been identified by researchers at Mount Sinai as predictors of both heart and kidney health in children without disease. The epidemiological study of Mexican children was published in February in the journal Epigenomics. For the first time, we measured in healthy children the associations between
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Today, the U.S. Food and Drug Administration approved Nulibry (fosdenopterin) for injection to reduce the risk of death due to Molybdenum Cofactor Deficiency Type A, a rare, genetic,  metabolic disorder that typically presents in the first few days of life, causing intractable seizures, brain injury and death. Today’s action marks the first FDA approval for
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Extremely low birth weight (ELBW) infants with moderate to large patent ductus arteriosus (PDA) may benefit from transcatheter PDA closure (TCPC) in the first four weeks of life, according to research published by Le Bonheur Cardiologist Ranjit Philip, MD, and Medical Director of Interventional Cardiac Imaging and Interventional Catheterization Laboratory Shyam Sathanandam, MD. Early PDA
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Ahead of Rare Disease Day (28 February), four leading children’s research institutions on three continents are joining forces to decipher pediatric illnesses, including rare diseases, and find better treatments. The four pediatric hospitals — Boston Children’s Hospital; UCL Great Ormond Street Institute for Child Health and Great Ormond Street Hospital (London); the Murdoch Children’s Research
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While the amazing regenerative power of the liver has been known since ancient times, the cells responsible for maintaining and replenishing the liver have remained a mystery. Now, research from the Children’s Medical Center Research Institute at UT Southwestern (CRI) has identified the cells responsible for liver maintenance and regeneration while also pinpointing where they
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