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Children treated for cancer with approaches such as chemotherapy can develop therapy-related myeloid neoplasms (a second type of cancer) with a dismal prognosis. Scientists at St. Jude Children’s Research Hospital have characterized the genomic abnormalities of 84 such myeloid neoplasms, with potential implications for early interventions to stop the disease. A paper detailing the work

Cisplatin is one of the most effective chemotherapy agents, used in just under half of pediatric cancer cases. Permanent hearing loss is a common side effect of this medication, but until now, studies have been too small and too varied to accurately characterize this risk. Today in The Lancet Child & Adolescent Health, investigators at

Since the onset of the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), millions of people have died, with well over a hundred million infections having been reported worldwide. Some groups are especially vulnerable to the virus, developing severe and progressive disease. The World Health Organization has identified

As the number of pregnant women using opioid drugs continues to rise, questions have been raised about the long-term health effects on children exposed to these drugs in the womb. Researchers at the University of Maryland School of Medicine now have preliminary but striking evidence that suggests that such exposure can cause long-lasting impairment in

Experts have spent decades warning us about the rising rates of childhood obesity, which has become an epidemic among recent generations in many places around the world, including Spain. The transition from the traditional Mediterranean diet to the consumption of processed foods with low nutritional value is a key contributor, with child-targeted advertising also partly

Brain volume, verbal IQ, and overall IQ are lower in children with Type 1 diabetes (T1D) than in children without diabetes, according to a new longitudinal study published in Diabetes Care, a journal of the American Diabetes Association. The nearly eight-year study, led by Nelly Mauras, MD, a clinical research scientist at Nemours Children’s Health

Anti-retroviral drugs are a vital tool in the prevention and treatment of HIV. A new study of pregnant women in Tanzania shows that life-long antiviral treatment also seems to prevent viral transmission from mother to baby. The results of the study, which was conducted in part by researchers at Karolinska Institutet in Sweden and published

Fusing the neck’s top two vertebrae can prevent repeat strokes in children with bow hunter syndrome, a rare condition that affects a handful of U.S. pediatric patients each year, UT Southwestern researchers suggest in a recent study. The finding, published online in Child’s Nervous System, offers a new way to treat these children and protect